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ZIRC
ZFIN ID: ZDB-GENE-030523-1
Gene Name: troponin C type 1a (slow)
Gene Symbol: tnnc1a
Sequence Ontology ID : SO:0000704

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Previous Names: cTnC (1), tnnc1, sil, zgc:103465

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(Including Attributions)
Location: Chr: 23 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have actin filament binding activity; calcium ion binding activity; and calcium-dependent protein binding activity. Involved in cardiac muscle contraction; cardiac ventricle development;  ...
GENE EXPRESSION
All Expression Data: 11 figures from 8 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:103465]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
az5 Small Deletion Unknown Unknown CRISPR
az6 Indel Unknown Unknown CRISPR
m656 Unknown Unknown Unknown ENU
sa14726 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa15521 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa25192 Point Mutation Unknown Splice Site ENU
    sk25 Small Deletion Unknown Unknown ENU
    Targeting reagents:
    DISEASE ASSOCIATED WITH tnnc1a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    dilated cardiomyopathy 1Z Cardiomyopathy, dilated, 1Z 611879
    hypertrophic cardiomyopathy 13 Cardiomyopathy, hypertrophic, 13 613243
    DISEASE ASSOCIATED WITH tnnc1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process response to activity (more)
    Cellular Component troponin complex (more)
    Molecular Function calcium ion binding (more)
    GO Terms (all 9)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA tnnc1a-201 (1) 1089
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM tnnc1a
    MARKER RELATIONSHIPS
    tnnc1aContained in: [BAC] CH211-117K14 (1) (order this)
    tnnc1aEncodes: [cDNA] MGC:103465 (1) (order this), MGC:192052 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_181498 (1) 1769bp
    Genomic GenBank:CR354596 (1) 172749bp
    Select Tool
    Polypeptide UniProtKB:Q5XJB2 (1) 161aa
    Sequence Clusters UniGene:87343 (1)
    Sequence Information (all 16)
    ORTHOLOGY for tnnc1a (Chr: 23)
    CITATIONS (45)