ZFIN ID: ZDB-GENE-030522-1
Gene Name: cardiac myosin light chain-1
Gene Symbol: cmlc1    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: laz (1), lazy susan (1), zgc:103441

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have calcium ion binding activity. Involved in heart contraction; heart morphogenesis; and myofibril assembly. Is expressed in heart primordium; mesoderm; pericardial region; and somite. Human ortholog(s) of this gene implicated in familial atrial fibrillation. Orthologous to human MYL4 (myosin light chain 4).
Genome Resources: Alliance (1),  Gene:64671 (1),  Ensembl(GRCz11):ENSDARG00000032976 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
az3 Indel Unknown Unknown CRISPR
az4 Insertion Unknown Unknown CRISPR
m647 Point Mutation Unknown Premature Stop ENU
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
CRISPR1-cmlc1 1
MO1-cmlc1 N/A 1
MO2-cmlc1 N/A 4
DISEASE ASSOCIATED WITH cmlc1 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH cmlc1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process cardiac muscle tissue development (more)
Molecular Function calcium ion binding (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA cmlc1-201 (1)    Ensembl 796
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM cmlc1
Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
Tg(kop:mCherryF-nanos3-UTR,cmlc1:EGFP) cmlc1kop EGFPmCherrynanos3UTR Danio rerio 1 1
MARKER RELATIONSHIPS
cmlc1 Contained in: [BAC] DKEY-43F11 (1) (order this)
cmlc1 Encodes: [EST] IMAGE:6903402 (1)
[cDNA] MGC:103441 (1), MGC:192170 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_131692 (1) 822 nt
Genomic GenBank:AL845516 (1) 205826 nt Blast at MegaBLAST
Polypeptide UniProtKB:B0R0F7 (1) 196 aa
Sequence Information (all 16)
ORTHOLOGY for cmlc1 ( Chr: 5 )
CITATIONS (61)