ZFIN ID: ZDB-GENE-030513-3
Gene Name: thyroid stimulating hormone, beta subunit, a
Gene Symbol: tshba
Previous Name: tshb (1)
Location: Chr: 6 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 22 figures from 15 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Larval:Days 14-20 (14d-21d, 6.2mm, 10 teeth)
  adenohypophyseal placode, adenohypophysis, anatomical structure, hypophysis (all 9) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH tshba HUMAN ORTHOLOG 
Disease Ontology Term OMIM Term OMIM Phenotype ID
congenital hypothyroidism Hypothryoidism, congenital, nongoitrous 4 275100
GENE ONTOLOGY 
Ontology GO Term
Cellular Component extracellular region (more)
Molecular Function hormone activity (more)
GO Terms (all 2)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001545 (1)
  • InterPro:IPR006208 (1)
  • InterPro:IPR018245 (1)
  • InterPro:IPR029034 (1)
  • PROSITE:PS00261 (1)
  • PROSITE:PS00689 (1)
  • Pfam:PF00007 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA tshba-001 (1) 826
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM tshba
    Tg(-2.5tshb:EGFP), Tg(tshb:EGFP)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    tshbaContained in: [BAC] CH211-105J21 (1) (order this)
    tshbaEncodes: [cDNA] MGC:193962 (1) (order this), MGC:193992 (1) (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_181494 (1) 816bp
    Genomic GenBank:BX005150 (1) 167946bp
    Select Tool
    Polypeptide UniProtKB:B3DJU0 (1) 148aa
    Sequence Clusters UniGene:88634 (1)
    Sequence Information (all 16)
    OTHER tshba GENE PAGES 
  • Gene:353223 (1)
  • VEGA:OTTDARG00000019922 (1)
  • Ensembl(GRCz10):ENSDARG00000033726 (1)
  • ORTHOLOGY for tshba (Chr: 6) 
    Species Symbol Chromosome Accession # Evidence
    Human TSHB 1
  • Gene:7252
  • OMIM:188540
  • HGNC:12372
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Mouse Tshb 3
  • MGI:98848
  • Gene:22094
  • Amino acid sequence comparison (1)
    Download Curated Orthology
    CITATIONS (71)