ZFIN ID: ZDB-GENE-030513-3
Gene Name: thyroid stimulating hormone, beta subunit, a
Gene Symbol: tshba
Previous Name: tshb (1)
Location: Chr: 6   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 21 figures from 14 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Larval:Days 14-20 (14d-21d, 6.2mm, 10 teeth)
  adenohypophyseal placode, adenohypophysis, anatomical structure, hypophysis (all 9) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH tshba HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
congenital hypothyroidism Hypothryoidism, congenital, nongoitrous 4 275100
GENE ONTOLOGY
Ontology GO Term
Cellular Component extracellular region (more)
Molecular Function hormone activity (more)
GO Terms (all 2)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001545 (1)
  • InterPro:IPR006208 (1)
  • InterPro:IPR018245 (1)
  • InterPro:IPR029034 (1)
  • PROSITE:PS00261 (1)
  • PROSITE:PS00689 (1)
  • Pfam:PF00007 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA tshb-001 (1) 826
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM tshba
    Tg(-2.5tshb:EGFP), Tg(tshb:EGFP)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    tshba Contained in: [BAC] CH211-105J21 (1) (order this)
    tshba Encodes: [cDNA] MGC:193962 (1) (order this), MGC:193992 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_181494 (1) 816 bp
    Genomic GenBank:BX005150 (1) 167946 bp
    Select Tool
    Polypeptide UniProtKB:B3DJU0 (1) 148 aa
    Sequence Clusters UniGene:88634 (1)
    Sequence Information (all 16)
    OTHER tshba GENE PAGES
  • Gene:353223 (1)
  • VEGA:OTTDARG00000019922 (1)
  • Ensembl(Zv9):ENSDARG00000033726 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish tshba 6  
    Human TSHB 1 (1p13)
  • OMIM:188540
  • Gene:7252
  • Mouse Tshb 3 ( 45.25 cM)
  • MGI:98848
  • Gene:22094
  • Orthology Details
    CITATIONS (53)