Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-030513-3
Gene Name: thyroid stimulating hormone, beta subunit
Gene Symbol: tshb
Location: Chr: 6   Details
GENE EXPRESSION
All Expression Data: 20 figures from 13 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Larval:Days 14-20 (14d-21d, 6.2mm, 10 teeth)
  adenohypophyseal placode, adenohypophysis, anatomical structure, hypophysis (all 8) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS No data available
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Hypothryoidism, congenital, nongoitrous 4 275100
GENE ONTOLOGY
Ontology GO Term
Cellular Component extracellular region (more)
Molecular Function hormone activity (more)
GO Terms (all 2)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001545 (1)
  • InterPro:IPR006208 (1)
  • InterPro:IPR018245 (1)
  • InterPro:IPR029034 (1)
  • PROSITE:PS00261 (1)
  • PROSITE:PS00689 (1)
  • Pfam:PF00007 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA tshb-001 (1) 826
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM tshb
    Tg(-2.5tshb:EGFP), Tg(tshb:EGFP)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    tshb Contained in: [BAC] CH211-105J21 (1) (order this)
    tshb Encodes: [cDNA] MGC:193962 (1) (order this), MGC:193992 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_181494 (1) 816 bp
    Genomic GenBank:BX005150 (1) 167946 bp
    Select Tool
    Polypeptide UniProtKB:B3DJU0 (1) 148 aa
    Sequence Clusters UniGene:88634 (1)
    Sequence Information (all 16)
    OTHER tshb GENE PAGES
  • Gene:353223 (1)
  • VEGA:OTTDARG00000019922 (1)
  • Ensembl(Zv9):ENSDARG00000033726 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA
    Zebrafish tshb 6  
    Human TSHB 1 (1p13)
  • OMIM:188540
  • Gene:7252
  • Mouse Tshb 3 ( 45.25 cM)
  • MGI:98848
  • Gene:22094
  • Orthology Details
    CITATIONS (48)