ZFIN ID: ZDB-GENE-030429-21
Gene Name: myelin basic protein b
Gene Symbol: mbpb    Nomenclature History

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Previous Names: Golli (1), sb:cb183 (1), si:dkey-241k19.2, wu:fb71b08

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to be a structural constituent of myelin sheath. Localizes to myelin sheath and plasma membrane. Is expressed in nervous system and polster. Human ortholog(s) of this gene implicated in multiple sclerosis. Orthologous to human MBP (myelin basic protein).
Genome Resources: Alliance (1),  Gene:368319 (1),  Ensembl(GRCz11):ENSDARG00000089413 (2)
GENE EXPRESSION
All Expression Data: 4 figures from 3 publications
Directly Submitted Expression Data: 2 figures (2 images) from Thisse et al., 2001 [cb183]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6406 Point Mutation Unknown Premature Stop ENU
PHENOTYPE No data available
DISEASE ASSOCIATED WITH mbpb HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH mbpb VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Cellular Component myelin sheath (more)
Molecular Function structural constituent of myelin sheath (more)
GO Terms (all 3)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA mbpb-201 (1)    Ensembl 828
mbpb-202 (1)    Ensembl 1960
mbpb-203 (1)    Ensembl 883
mbpb-205 (1)    Ensembl 1983
ncRNA mbpb-005 (1) 704
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM mbpb No data available
MARKER RELATIONSHIPS
mbpb Contained in: [BAC] CH211-198O19 (1), DKEY-241K19 (1) (order this)
mbpb Encodes: [EST] cb183 (1), fb71b08, IMAGE:3815793
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001271459 (1)
Genomic GenBank:AL845419 (1) 176379 nt
Select Tool
Polypeptide UniProtKB:E7EYA2 (1) 133 aa
Sequence Information (all 26)
ORTHOLOGY for mbpb ( Chr: 16 )
CITATIONS (20)