ZFIN ID: ZDB-GENE-030328-29
Gene Name: cysteinyl-tRNA synthetase 1
Gene Symbol: cars1    Nomenclature History

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Previous Names: cars, sb:cb71 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have ATP binding activity and cysteine-tRNA ligase activity. Predicted to be involved in cysteinyl-tRNA aminoacylation. Predicted to localize to cytoplasm. Is expressed in several structures, including eye; hatching gland; pectoral fin musculature; polster; and tail bud. Orthologous to human CARS1 (cysteinyl-tRNA synthetase 1).
Genome Resources: Alliance (1),  Gene:368284 (1),  Ensembl(GRCz11):ENSDARG00000036164 (2)
DISEASE ASSOCIATED WITH cars1 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Microcephaly, developmental delay, and brittle hair syndrome 618891
DISEASE ASSOCIATED WITH cars1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process cysteinyl-tRNA aminoacylation (more)
Cellular Component cytoplasm (more)
Molecular Function aminoacyl-tRNA ligase activity (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA cars-201 (1)    Ensembl 2496
cars-202 (1)    Ensembl 3000
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM cars1 No data available
MARKER RELATIONSHIPS
cars1 Contained in: [BAC] CH211-251J8 (1)
cars1 Encodes: [EST] cb71 (1) (order this), IMAGE:7152122 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001118900 (1) 3181 nt
Genomic GenBank:AL935207 (1) 146351 nt
Select Tool
Polypeptide UniProtKB:E7FDV9 (1) 824 aa
Sequence Information (all 14)
ORTHOLOGY for cars1 ( Chr: 7 )
CITATIONS (26)