Gene

gli1

ID
ZDB-GENE-030321-1
Name
GLI family zinc finger 1
Symbol
gli1 Nomenclature History
Previous Names
  • detour
  • dtr
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including muscle cell fate specification; nervous system development; and positive regulation of smoothened signaling pathway. Localizes to Hedgehog signaling complex. Is expressed in several structures, including central nervous system; head; neural plate; neural tube; and paraxial mesoderm. Orthologous to human GLI1 (GLI family zinc finger 1).
Genome Resources
Note
None
Expression
All Expression Data
47 figures from 37 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
28 figures from 13 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gli1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Polydactyly, postaxial, type A8 618123
Polydactyly, preaxial I 174400
Associated With gli1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR013087 Zinc finger C2H2-type
Family IPR032850 Zinc finger protein GLI1
Family IPR043359 C2H2-type zinc-finger protein GLI-like
Homologous_superfamily IPR036236 Zinc finger C2H2 superfamily
Domain Details Per Protein
Protein Length C2H2-type zinc-finger protein GLI-like Zinc finger C2H2 superfamily Zinc finger C2H2-type Zinc finger protein GLI1
UniProtKB:F1QAC4 1404
UniProtKB:Q800Z9 1404
Transcripts
Genome Browsers
No data available
Interactions and Pathways
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations