ZFIN is now using GRCz12tu for Genomic Data
Gene
p2rx2
- ID
- ZDB-GENE-030319-2
- Name
- purinergic receptor P2X, ligand-gated ion channel, 2
- Symbol
- p2rx2 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables extracellularly ATP-gated monoatomic cation channel activity. Acts upstream of or within monoatomic ion transport. Predicted to be located in endomembrane system; membrane; and postsynapse. Predicted to be part of signaling receptor complex. Predicted to be active in plasma membrane. Is expressed in Rohon-Beard neurons and cranial ganglion. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 41. Orthologous to human P2RX2 (purinergic receptor P2X 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Appelbaum et al., 2007
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant nonsyndromic deafness 41 | Alliance | Deafness, autosomal dominant 41 | 608224 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | ATP P2X receptor-like | P2X2 purinoceptor | P2X purinoreceptor | P2X purinoreceptor extracellular domain superfamily |
|---|---|---|---|---|---|---|
| UniProtKB:Q7SZL9 | InterPro | 400 | ||||
| UniProtKB:A0AC58JHU3 | InterPro | 330 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers