Gene

mcamb

ID

ZDB-GENE-030219-213

Name

melanoma cell adhesion molecule b

Symbol

mcamb Nomenclature History

Previous Names

mcam (1)
cd146 (1)
gicerin (1)
id:ibd3512

Type

protein_coding_gene

Location

Chr: 15 Mapping Details/Browsers

Description

Involved in several processes, including axon regeneration; epithelial cilium movement involved in determination of left/right asymmetry; and vasculature development. Predicted to localize to integral component of membrane. Is expressed in several structures, including Kupffer's vesicle; blood island; cardiovascular system; forerunner cell group; and neurons. Orthologous to human MCAM (melanoma cell adhesion molecule).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

15 figures from 10 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 12 figures from 5 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mcamb Human Ortholog

No data available

Associated With mcamb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003598	Immunoglobulin subtype 2
Domain	IPR003599	Immunoglobulin domain subtype
Domain	IPR007110	Immunoglobulin-like domain
Domain	IPR013106	Immunoglobulin V-set domain
Domain	IPR013162	CD80-like, immunoglobulin C2-set
Family	IPR051116	Cell Surface Receptors and Adhesion Molecules
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR036179	Immunoglobulin-like domain superfamily