ZFIN ID: ZDB-GENE-030219-15
Gene Name: adenosine deaminase RNA specific B1b
Gene Symbol: adarb1b    Nomenclature History

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Previous Names: id:ibd3153 (1), si:ch211-268b13.2 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have double-stranded RNA adenosine deaminase activity; double-stranded RNA binding activity; and tRNA-specific adenosine deaminase activity. Predicted to be involved in RNA processing and adenosine to inosine editing. Predicted to localize to the cytoplasm and nucleolus. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis. Is expressed in blood island; blood vessel; central nervous system; and immature eye. Orthologous to human ADARB1 (adenosine deaminase RNA specific B1).
Genome Resources: Alliance (1),  Gene:558759 (1),  Ensembl(GRCz11):ENSDARG00000003544 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa11903 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21595 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH adarb1b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH adarb1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process RNA processing (more)
    Cellular Component cytoplasm (more)
    Molecular Function adenosine deaminase activity (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR002466 Adenosine deaminase/editase
    Domain IPR014720 Double-stranded RNA-binding domain
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA adarb1b-201 (1)    Ensembl 2471
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM adarb1b No data available
    MARKER RELATIONSHIPS
    adarb1b Contained in: [BAC] CH211-268B13 (1)
    adarb1b Encodes: [EST] ibd3153
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_021479018 (1)
    Genomic GenBank:BX005108 (1) 171835 bp
    Select Tool
    Polypeptide UniProtKB:E9QJK5 (1) 699 aa
    Sequence Information (all 21)
    ORTHOLOGY for adarb1b ( Chr: 9 )
    CITATIONS (20)