Gene

bmper

ID

ZDB-GENE-030219-146

Name

BMP binding endothelial regulator

Symbol

bmper Nomenclature History

Previous Names

Crossveinless 2 (1)
cv2 (1)
cvl2 (1)
id:ibd5071 (1)

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Exhibits extracellular matrix binding activity. Involved in several processes, including animal organ development; regulation of BMP signaling pathway; and regulation of angiogenesis. Localizes to extracellular matrix and extracellular space. Is expressed in several structures, including endoderm; head; mesoderm; nervous system; and pectoral fin. Orthologous to human BMPER (BMP binding endothelial regulator).

Genome Resources

Note

None

Expression

All Expression Data

20 figures from 11 publications

Cross-Species Comparison

High Throughput Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 9 figures from 5 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With bmper Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Diaphanospondylodysostosis	608022

Associated With bmper Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001007	VWFC domain
Domain	IPR001846	von Willebrand factor, type D domain
Domain	IPR002919	Trypsin Inhibitor-like, cysteine rich domain
Domain	IPR014853	Uncharacterised domain, cysteine-rich
Homologous_superfamily	IPR036084	Serine protease inhibitor-like superfamily

Domain Details Per Protein

Protein	Length	Serine protease inhibitor-like superfamily	Trypsin Inhibitor-like, cysteine rich domain	Uncharacterised domain, cysteine-rich	von Willebrand factor, type D domain	VWFC domain
UniProtKB:A0A0R4IGC8 InterPro	663
UniProtKB:A0A0R4IIF4 InterPro	564
UniProtKB:A6H8K2 InterPro	668
UniProtKB:A0A0B5JK69 InterPro	609
UniProtKB:Q5D734 InterPro PDB	668
UniProtKB:A0A0R4IDS8 InterPro	667