ZFIN ID: ZDB-GENE-030131-9960
Gene Name: SAM and SH3 domain containing 1a
Gene Symbol: sash1a    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: fi33a01, ik:tdsubc_2e1, si:dkey-264g21.1, tdsubc_2e1, wu:fi33a01 (1), xx:tdsubc_2e1

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 20 Mapping Details/Browsers
Description: Human ortholog(s) of this gene implicated in dyschromatosis universalis hereditaria. Is expressed in forebrain; hindbrain; and midbrain. Orthologous to human SASH1 (SAM and SH3 domain containing 1).
Genome Resources: Alliance (1),  Gene:557132 (1),  Ensembl(GRCz11):ENSDARG00000007179 (2)
GENE EXPRESSION
All Expression Data: Fig. 1 from Shamay-Ramot et al., 2015
Wild-type Stages, Structures: Larval:Day 6 (144.0h-168.0h) to Larval:Day 6 (144.0h-168.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la010225Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la021550Tg Transgenic Insertion Unknown Unknown DNA
    la028245Tg Transgenic Insertion Unknown Unknown DNA
    sa10306 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa11349 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa37072 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa43477 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa43478 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH sash1a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    dyschromatosis universalis hereditaria Alliance Dyschromatosis universalis hereditaria 1 127500
    ?Cancer, alopecia, pigment dyscrasia, onychodystrophy, and keratoderma 618373
    DISEASE ASSOCIATED WITH sash1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY No data available
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR001452 SH3 domain
    Domain IPR001660 Sterile alpha motif domain
    Homologous_superfamily IPR013761 Sterile alpha motif/pointed domain superfamily
    Family IPR021090 SAM/SH3 domain-containing
    Domain IPR035720 SAM and SH3 domain-containing protein 1, SH3 domain
    Homologous_superfamily IPR036028 SH3-like domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA sash1a-201 (1)    Ensembl 7137
    sash1a-203 (1)    Ensembl 3742
    sash1a-204 (1)    Ensembl 780
    sash1a-205 (1)    Ensembl 718
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM sash1a No data available
    MARKER RELATIONSHIPS
    sash1a Contained in: [BAC] CH211-279M15 (1), DKEY-220E22 (1) (order this), DKEY-264G21 (1) (order this)
    sash1a Encodes: [EST] fi33a01, tdsubc_2e1
    [cDNA] MGC:162728 (1), MGC:198337 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001044819 (1) 5770 bp
    Genomic GenBank:BX511140 (1) 166153 bp
    Select Tool
    Polypeptide UniProtKB:Q5TZ33 (1) 1192 aa
    Sequence Information (all 35)
    ORTHOLOGY for sash1a ( Chr: 20 )
    CITATIONS (23)