ZFIN ID: ZDB-GENE-030131-977
Gene Name: chaperonin containing TCP1, subunit 5 (epsilon)
Gene Symbol: cct5    Nomenclature History

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Previous Names: TCP-1 epsilon (1), unm tf212, unm_tf212, wu:fb54h08

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 24 Mapping Details/Browsers
Description: Predicted to have ATP binding activity and unfolded protein binding activity. Involved in skeletal muscle thin filament assembly. Predicted to localize to chaperonin-containing T-complex. Is expressed in several structures, including epidermis; nervous system; pharyngeal arch 3-7 skeleton; proliferative region; and yolk syncytial layer. Orthologous to human CCT5 (chaperonin containing TCP1 subunit 5).
Genome Resources: Alliance (1),  Gene:322258 (1),  Ensembl(GRCz11):ENSDARG00000045399 (2)
GENE EXPRESSION
All Expression Data: 14 figures from 4 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7147715]
  12 figures (5 images) from Rauch et al., 2003 [fb19f06]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi2972bTg Transgenic Insertion Intron 1 Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tf212b Point Mutation Exon 9 Missense
  • European Zebrafish Resource Center (EZRC) (order this)
  • u762 Point Mutation Unknown Unknown ENU
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-cct5 N/A 1
    MO2-cct5 N/A 1
    DISEASE ASSOCIATED WITH cct5 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Neuropathy, hereditary sensory, with spastic paraplegia 256840
    DISEASE ASSOCIATED WITH cct5 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process skeletal muscle thin filament assembly (more)
    Cellular Component cytoplasm (more)
    Molecular Function ATP binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cct5-201 (1)    Ensembl 1906
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cct5
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(-1.8cct5:EGFP,cryaa:mCherry) cct5cryaa EGFPmCherry Danio rerio 1 1
    MARKER RELATIONSHIPS
    cct5 Contained in: [BAC] DKEY-30N5 (1) (order this)
    cct5 Encodes: [EST] fb19f06 (1) (order this), fb54h08, IMAGE:7147715 (1)
    [cDNA] MGC:77639 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_212613 (1) 1896 nt
    Genomic GenBank:BX469922 (1) 200409 nt Blast at MegaBLAST
    Polypeptide UniProtKB:Q6NVI6 (1) 541 aa
    Sequence Information (all 16)
    ORTHOLOGY for cct5 ( Chr: 24 )
    CITATIONS (38)