Gene

lztr1

ID
ZDB-GENE-030131-9564
Name
leucine-zipper-like transcription regulator 1
Symbol
lztr1 Nomenclature History
Previous Names
  • fj87c05
  • si:dkey-98f17.2 (1)
  • wu:fj87c05
  • zgc:158250
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to localize to Golgi apparatus. Human ortholog(s) of this gene implicated in Noonan syndrome 10; Noonan syndrome 2; and neurilemmomatosis. Orthologous to human LZTR1 (leucine zipper like transcription regulator 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With lztr1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
neurilemmomatosis Alliance {Schwannomatosis-2, susceptibility to} 615670
Noonan syndrome 2 Alliance Noonan syndrome 2 605275
Noonan syndrome 10 Alliance Noonan syndrome 10 616564
Associated With lztr1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000210 BTB/POZ domain
Homologous_superfamily IPR011333 SKP1/BTB/POZ domain superfamily
Homologous_superfamily IPR015915 Kelch-type beta propeller
Repeat IPR006652 Kelch repeat type 1
Repeat IPR011498 Kelch repeat type 2
Domain Details Per Protein
Protein Length BTB/POZ domain Kelch repeat type 1 Kelch repeat type 2 Kelch-type beta propeller SKP1/BTB/POZ domain superfamily
UniProtKB:A9JRR0 776
UniProtKB:A0A2R8QN10 776
UniProtKB:F1R533 783
UniProtKB:A1L1Q7 776
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations