ZFIN ID: ZDB-GENE-030131-9537
Gene Name: family with sequence similarity 49 member Ba
Gene Symbol: fam49ba    Nomenclature History

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Previous Names: fam49b, fj85c11, wu:fj85c11, zgc:64118 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to be involved in positive regulation of T cell activation. Is expressed in epidermis; periderm; pharyngeal arch 3-7 skeleton; and pronephros. Orthologous to human CYRIB (CYFIP related Rac1 interactor B).
Genome Resources: Alliance (1),  Gene:337591 (1),  Ensembl(GRCz11):ENSDARG00000020929 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (10 images) from Thisse et al., 2004 [MGC:64118]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa19797 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH fam49ba HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH fam49ba VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of T cell activation (more)
    Cellular Component cellular_component (more)
    Molecular Function molecular_function (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA fam49ba-201 (1)    Ensembl 1764
    fam49ba-204 (1)    Ensembl 1180
    fam49ba-207 (1)    Ensembl 829
    ncRNA fam49ba-003 (1)    Ensembl 592
    fam49ba-004 (1)    Ensembl 533
    fam49ba-006 (1)    Ensembl 598
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM fam49ba No data available
    MARKER RELATIONSHIPS
    fam49ba Contained in: [BAC] CH211-139K8 (1), CH211-160I2 (1), DKEY-18O1 (1) (order this)
    fam49ba Encodes: [EST] fj85c11
    [cDNA] MGC:64118 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_200070 (1) 1455 nt
    Genomic GenBank:BX663499 (1) 195369 nt
    Select Tool
    Polypeptide UniProtKB:Q6TLE5 (1) 325 aa
    Sequence Information (all 23)
    ORTHOLOGY for fam49ba ( Chr: 2 )
    CITATIONS (21)