Gene

yrk

ID
ZDB-GENE-030131-9517
Name
Yes-related kinase
Symbol
yrk Nomenclature History
Previous Names
  • fj84d04
  • wu:fj84d04 (1)
  • zgc:92165
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to have non-membrane spanning protein tyrosine kinase activity and signaling receptor binding activity. Involved in macrophage chemotaxis. Predicted to localize to extrinsic component of cytoplasmic side of plasma membrane. Is expressed in blood island; cardiovascular system; head; mesoderm; and post-vent region.
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
13 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With yrk Human Ortholog
No data available
Associated With yrk Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008266 Tyrosine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Domain IPR000980 SH2 domain
Domain IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domain
Domain IPR001452 SH3 domain
Domain IPR020635 Tyrosine-protein kinase, catalytic domain
Domain IPR035693 Tyrosine-protein kinase Fgr, SH2 domain
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR036028 SH3-like domain superfamily
Homologous_superfamily IPR036860 SH2 domain superfamily
Domain Details Per Protein
Protein Length Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily Serine-threonine/tyrosine-protein kinase, catalytic domain SH2 domain SH2 domain superfamily SH3 domain SH3-like domain superfamily Tyrosine-protein kinase, active site Tyrosine-protein kinase, catalytic domain Tyrosine-protein kinase Fgr, SH2 domain
UniProtKB:F8W2A7 137
UniProtKB:I3IS06 219
UniProtKB:Q66HZ1 528
UniProtKB:A5WWJ8 27
UniProtKB:A5WWJ6 528
UniProtKB:Q8AWF1 525
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations