ZFIN ID: ZDB-GENE-030131-9435
Gene Name: phospholipase C, delta 1b
Gene Symbol: plcd1b    Nomenclature History

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Previous Names: DrPLC-delta 1B, fj78d10, wu:fj78d10, zgc:55868

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have phosphatidylinositol phospholipase C activity. Predicted to be involved in inositol trisphosphate biosynthetic process; phosphatidylinositol-mediated signaling; and release of sequestered calcium ion into cytosol. Is expressed in lens; neuromast; and solid lens vesicle. Human ortholog(s) of this gene implicated in nonsyndromic congenital nail disorder 3. Orthologous to human PLCD1 (phospholipase C delta 1).
Genome Resources: Alliance (1),  Gene:337489 (1),  Ensembl(GRCz11):ENSDARG00000034080 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (7 images) from Thisse et al., 2005 [eu915]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Hatching:Long-pec (48.0h-60.0h)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH plcd1b HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
nonsyndromic congenital nail disorder 3 Alliance Nail disorder, nonsyndromic congenital, 3, (leukonychia) 151600
DISEASE ASSOCIATED WITH plcd1b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process intracellular signal transduction (more)
Molecular Function hydrolase activity (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
Browsers: NCBI
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM plcd1b No data available
MARKER RELATIONSHIPS
plcd1b Contained in: [BAC] CH211-12E1 (1)
plcd1b Encodes: [EST] eu915 (1), fj78d10
[cDNA] MGC:55868 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_200068 (1) 3056 nt
Genomic GenBank:BX000484 (1) 158932 nt
Select Tool
Polypeptide UniProtKB:F1R8S3 (1) 749 aa
Sequence Information (all 24)
ORTHOLOGY for plcd1b ( Chr: 2 )
CITATIONS (25)