ZFIN ID: ZDB-GENE-030131-9345
Gene Name: ribosome biogenesis regulator 1 homolog
Gene Symbol: rrs1    Nomenclature History

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Previous Names: fj66c04, wu:fj66c04, zgc:66358 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 24 Mapping Details/Browsers
Description: Predicted to be involved in endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); ribosomal large subunit biogenesis; and ribosomal large subunit export from nucleus. Predicted to localize to nucleolus and preribosome, large subunit precursor. Is expressed in several structures, including eye; midbrain; musculature system; pectoral fin bud; and segmental plate. Orthologous to human RRS1 (ribosome biogenesis regulator 1 homolog).
Genome Resources: Alliance (1),  Gene:337399 (1),  Ensembl(GRCz11):ENSDARG00000003941 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la022930Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44140 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH rrs1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH rrs1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process ribosome biogenesis (more)
    Cellular Component nucleus (more)
    Molecular Function molecular_function (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA rrs1-201 (1)    Ensembl 2129
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM rrs1 No data available
    MARKER RELATIONSHIPS
    rrs1 Contained in: [BAC] DKEY-162H1 (1) (order this)
    rrs1 Encodes: [EST] fj66c04
    [STS] chunp30272
    [cDNA] MGC:66358 (1), MGC:173898 (1), MGC:191331 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_200062 (1) 1350 nt
    Genomic GenBank:BX470095 (1) 209513 nt Blast at MegaBLAST
    Polypeptide UniProtKB:A8KBQ7 (1) 346 aa
    Sequence Information (all 22)
    ORTHOLOGY for rrs1 ( Chr: 24 )
    CITATIONS (31)