Gene
sulf1
- ID
- ZDB-GENE-030131-9242
- Name
- sulfatase 1
- Symbol
- sulf1 Nomenclature History
- Previous Names
-
- wu:fk14e08
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Is predicted to enable N-acetylglucosamine-6-sulfatase activity and glycosaminoglycan binding activity. Involved in several processes, including glomerular basement membrane development; positive regulation of vascular endothelial growth factor production; and regulation of signal transduction. Acts upstream of or within with a positive effect on epithelial structure maintenance. Acts upstream of or within several processes, including neuromast deposition; regionalization; and vasculogenesis. Predicted to be located in Golgi stack and extracellular space. Is expressed in several structures, including cardiovascular system; central nervous system; head; hypochord; and somite. Orthologous to human SULF1 (sulfatase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 23 figures from 4 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Alkaline-phosphatase-like, core domain superfamily | Extracellular sulfatase, C-terminal | Sulfatase, conserved site | Sulfatase, N-terminal |
|---|---|---|---|---|---|
|
UniProtKB:Q6EFA1
|
1099 |
Interactions and Pathways
No data available
Plasmids
No data available