Gene

sulf1

ID
ZDB-GENE-030131-9242
Name
sulfatase 1
Symbol
sulf1 Nomenclature History
Previous Names
  • wu:fk14e08
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Is predicted to enable N-acetylglucosamine-6-sulfatase activity and glycosaminoglycan binding activity. Involved in several processes, including glomerular basement membrane development; positive regulation of vascular endothelial growth factor production; and regulation of signal transduction. Acts upstream of or within with a positive effect on epithelial structure maintenance. Acts upstream of or within several processes, including neuromast deposition; regionalization; and vasculogenesis. Predicted to be located in Golgi stack and extracellular space. Is expressed in several structures, including cardiovascular system; central nervous system; head; hypochord; and somite. Orthologous to human SULF1 (sulfatase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
9 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
23 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sulf1 Human Ortholog
No data available
Associated With sulf1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR024607 Sulfatase, conserved site
Domain IPR000917 Sulfatase, N-terminal
Domain IPR024609 Extracellular sulfatase, C-terminal
Homologous_superfamily IPR017850 Alkaline-phosphatase-like, core domain superfamily
Domain Details Per Protein
Protein Length Alkaline-phosphatase-like, core domain superfamily Extracellular sulfatase, C-terminal Sulfatase, conserved site Sulfatase, N-terminal
UniProtKB:Q6EFA1 1099
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations