ZFIN ID: ZDB-GENE-110429-1
Gene Name: CD44 molecule (Indian blood group) a
Gene Symbol: cd44a    Nomenclature History

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Previous Names: cd44, fa99e04, wu:fa99e04

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to contribute to cytokine receptor activity. Involved in vasculature development. Predicted to localize to basolateral plasma membrane and macrophage migration inhibitory factor receptor complex. Human ortholog(s) of this gene implicated in breast carcinoma (multiple); carcinoma (multiple); and prostate cancer. Orthologous to human CD44 (CD44 molecule (Indian blood group)).
Genome Resources: Alliance (1),  Gene:797357 (1),  Ensembl(GRCz11):ENSDARG00000087863 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Hatching:Long-pec (48.0h-60.0h) to Larval:Days 7-13 (168.0h-14d, 4.5mm, 8 teeth)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ihb231 Small Deletion Exon 2 Unknown CRISPR
ihb232 Insertion Exon 2 Unknown CRISPR
sa21059 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34175 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-cd44a 1
    MO1-cd44a N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cd44a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    [Blood group, Indian system] 609027
    DISEASE ASSOCIATED WITH cd44a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process vasculature development (more)
    Cellular Component cell projection (more)
    Molecular Function hyaluronic acid binding (more)
    GO Terms (all 14)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cd44a-201 (1)    Ensembl 1782
    ncRNA cd44a-002 (1)    Ensembl 540
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM cd44a No data available
    MARKER RELATIONSHIPS
    cd44a Contained in: [BAC] CH211-102L7
    cd44a Encodes: [EST] fa99e04
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_001922456 (1) 1834 nt
    Genomic GenBank:CR318591 (1) 109921 nt
    Select Tool
    Polypeptide UniProtKB:E7F6T0 (1) 392 aa
    Sequence Information (all 11)
    ORTHOLOGY for cd44a ( Chr: 7 )
    CITATIONS (25)