Gene

mov10b.1

ID
ZDB-GENE-030131-9089
Name
Moloney leukemia virus 10b, tandem duplicate 1
Symbol
mov10b.1 Nomenclature History
Previous Names
  • fa99a10
  • si:dkeyp-38g6.2
  • wu:fa99a10
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have RNA binding activity. Predicted to be involved in mRNA cleavage involved in gene silencing by miRNA. Predicted to localize to P granule; P-body; and cytosol. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human MOV10 (Mov10 RISC complex RNA helicase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mov10b.1 Human Ortholog
No data available
Associated With mov10b.1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003593 AAA+ ATPase domain
Domain IPR041677 DNA2/NAM7 helicase, helicase domain
Domain IPR041679 DNA2/NAM7 helicase-like, C-terminal
Family IPR026122 Helicase MOV-10
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length AAA+ ATPase domain DNA2/NAM7 helicase, helicase domain DNA2/NAM7 helicase-like, C-terminal Helicase MOV-10 P-loop containing nucleoside triphosphate hydrolase
UniProtKB:Q1LXK4 1013
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Note
mov10b.1 and mov10b.2 appear to be the result of a tandem duplication with sequence identity and conserved synteny to human MOV10 and mouse Mov10. Zebrafish mov10a is the genome duplicate of the ancestral mov10b gene.
Citations