ZFIN ID: ZDB-GENE-030131-9077
Gene Name: methyl-CpG binding domain protein 3a
Gene Symbol: mbd3a    Nomenclature History

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Previous Name: wu:fa98f07

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have methyl-CpG binding activity. Predicted to be involved in DNA methylation-dependent heterochromatin assembly and negative regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in blastomere and pharyngeal arch 3-7 skeleton. Orthologous to human MBD3 (methyl-CpG binding domain protein 3).
Genome Resources: Alliance (1),  Gene:337133 (1),  Ensembl(GRCz11):ENSDARG00000061774 (2)
GENE EXPRESSION
All Expression Data: 15 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7139207]
  12 figures (22 images) from Rauch et al., 2003 [fb66a04]
  1 figure (1 image) from Thisse et al., 2004 [IMAGE:6908208]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-mbd3a N/A 2
PHENOTYPE No data available
DISEASE ASSOCIATED WITH mbd3a HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH mbd3a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Cellular Component host cell nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 4)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA mbd3a-202 (1)    Ensembl 998
mbd3a-203 (1)    Ensembl 830
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM mbd3a No data available
MARKER RELATIONSHIPS
mbd3a Contained in: [Fosmid] CH1073-325M22 (1)
mbd3a Encodes: [EST] fa98f07, fb66a04 (1) (order this), IMAGE:6908208 (1), IMAGE:7139207 (1)
[cDNA] MGC:86913 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_212769 (1) 1857 nt
Genomic GenBank:CU855938 (1) 30644 nt
Select Tool
Polypeptide UniProtKB:Q6IQ79 (1) 273 aa
Sequence Information (all 21)
ORTHOLOGY for mbd3a ( Chr: 2 )
CITATIONS (26)