ZFIN ID: ZDB-GENE-030131-899
Gene Name: acyl-CoA dehydrogenase, very long chain
Gene Symbol: acadvl
Previous Names: vlcad (1), fb52d04, wu:fb52d04, wu:fc75e01, zgc:64067
Location: Chr: 7 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 8 figures from 2 publications
Directly Submitted Expression Data: 6 figures (6 images) from Thisse et al., 2004 [MGC:64067]
  1 figure (1 image) from Thisse et al., 2004 [IMAGE:7162137]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  female organism liver, pectoral fin musculature, pronephric duct, whole organism
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa20905 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34039 Point Mutation Unknown Unknown ENU
    Targeting reagents: MO1-acadvl (1)
    PHENOTYPE
    Data: 2 figures from Carvalho et al., 2014
    Observed in: brain apoptotic process, brain cell proliferation, head
    DISEASE ASSOCIATED WITH acadvl HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    very long chain acyl-CoA dehydrogenase deficiency VLCAD deficiency 201475
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process head development (more)
    Cellular Component mitochondrion (more)
    Molecular Function acyl-CoA dehydrogenase activity (more)
    GO Terms (all 15)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR006089 (1)
  • InterPro:IPR006091 (1)
  • InterPro:IPR009075 (1)
  • InterPro:IPR009100 (1)
  • InterPro:IPR013786 (1)
  • PROSITE:PS00072 (1)
  • PROSITE:PS00073 (1)
  • Pfam:PF00441 (1)
  • Pfam:PF02770 (1)
  • Pfam:PF02771 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA acadvl-001 (1) 2572
    acadvl-002 (1) 3536
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM acadvl No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    acadvlContained in: [BAC] DKEY-33C9 (1) (order this)
    acadvlEncodes: [EST] fb52d04, fc75e01 (1), IMAGE:7162137 (1) (order this)
    [cDNA] MGC:64067 (1) (order this), MGC:174519 (1) (order this)
    acadvlHas Artifact: [EST] fo71e09
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_212611 (1) 2546bp
    Genomic GenBank:CR376787 (1) 217684bp Blast at MegaBLAST
    Polypeptide UniProtKB:A9JT52 (1) 659aa
    Sequence Clusters UniGene:3523 (1)
    Sequence Information (all 22)
    OTHER acadvl GENE PAGES
  • Gene:573723 (1)
  • VEGA:OTTDARG00000021705 (1)
  • Ensembl(GRCz10):ENSDARG00000016687 (1)
  • ORTHOLOGY for acadvl (Chr: 7)
    Species Symbol Chromosome Accession # Evidence
    Human ACADVL 17
  • Gene:37
  • OMIM:609575
  • HGNC:92
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Functional complementation (1)
    Download Curated Orthology
    CITATIONS (17)