ZFIN ID: ZDB-GENE-030131-879
Gene Name: protein disulfide isomerase family A, member 6
Gene Symbol: pdia6    Nomenclature History

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Previous Names: pdi-p5 (1), pdip5, wu:fb51h08, wu:fc09e09

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 20 Mapping Details/Browsers
Description: Predicted to have isomerase activity. Predicted to be involved in cell redox homeostasis. Is expressed in several structures, including axis; hatching gland; nervous system; pectoral fin musculature; and polster. Orthologous to human PDIA6 (protein disulfide isomerase family A member 6).
Genome Resources: Alliance (1),  Gene:322160 (1),  Ensembl(GRCz11):ENSDARG00000009001 (2)
GENE EXPRESSION
All Expression Data: 8 figures from 3 publications
Directly Submitted Expression Data: 6 figures (11 images) from Thisse et al., 2004 [MGC:55846]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa11858 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa37069 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-pdia6 N/A 1
    MO2-pdia6 N/A 2
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH pdia6 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH pdia6 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell redox homeostasis (more)
    Molecular Function isomerase activity (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA pdia6-201 (1)    Ensembl 2058
    ncRNA pdia6-002 (1) 480
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pdia6 No data available
    MARKER RELATIONSHIPS
    pdia6 Contained in: [BAC] DKEY-181F18 (1) (order this)
    pdia6 Contains: [SNP] rs3729032 (1), rs3729033 (1), rs3729034 (1), rs3729035 (1), rs3729036 (1)
    pdia6 Encodes: [EST] fb51h08, fc09e09
    [cDNA] MGC:55846 (1), MGC:192899 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_197933 (1) 1979 nt
    Genomic GenBank:BX000361 (1) 124183 nt
    Select Tool
    Polypeptide UniProtKB:Q803F3 (1) 440 aa
    Sequence Information (all 19)
    ORTHOLOGY for pdia6 ( Chr: 20 )
    CITATIONS (27)