ZFIN ID: ZDB-GENE-030131-8713
Gene Name: L3MBTL histone methyl-lysine binding protein 2
Gene Symbol: l3mbtl2    Nomenclature History

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Previous Names: im:7137244, wu:fb04e09, zgc:66491

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Predicted to have chromatin binding activity and methylated histone binding activity. Predicted to be involved in negative regulation of transcription, DNA-templated. Predicted to localize to nucleus. Orthologous to human L3MBTL2 (L3MBTL histone methyl-lysine binding protein 2).
Genome Resources: Alliance (1),  Gene:568473 (1),  Ensembl(GRCz11):ENSDARG00000056079 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:66491]
  1 figure (1 image) from Thisse et al., 2004 [IMAGE:7137244]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la018091Tg Transgenic Insertion Unknown Unknown DNA
la027311Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-l3mbtl2 N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH l3mbtl2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH l3mbtl2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of transcription, DNA-templated (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA l3mbtl2-201 (1)    Ensembl 3164
    l3mbtl2-202 (1)    Ensembl 1157
    l3mbtl2-203 (1)    Ensembl 959
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM l3mbtl2 No data available
    MARKER RELATIONSHIPS
    l3mbtl2 Contained in: [BAC] CH211-167D24 (1)
    l3mbtl2 Contains: [SNP] rs3728475 (1), rs3728476 (1)
    l3mbtl2 Encodes: [EST] fb04e09, IMAGE:7137244 (1)
    [cDNA] MGC:66491 (1), MGC:198085 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_200032 (1) 2810 nt
    Genomic GenBank:CR450737 (1) 156532 nt
    Select Tool
    Polypeptide UniProtKB:A0A2R8RWT1 (1) 805 aa
    Sequence Information (all 25)
    ORTHOLOGY for l3mbtl2 ( Chr: 12 )
    CITATIONS (27)