ZFIN ID: ZDB-GENE-030131-8631
Gene Name: ribosomal protein S14
Gene Symbol: rps14    Nomenclature History

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Previous Names: fa92e08, wu:fa92e08, zgc:73215

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Predicted to have mRNA 5'-UTR binding activity and small ribosomal subunit rRNA binding activity. Involved in chordate embryonic development and erythrocyte maturation. Predicted to localize to cytosolic small ribosomal subunit. Human ortholog(s) of this gene implicated in chromosome 5q deletion syndrome. Orthologous to human RPS14 (ribosomal protein S14).
Genome Resources: Alliance (1),  Gene:336687 (1),  Ensembl(GRCz11):ENSDARG00000036629 (2)
GENE EXPRESSION
All Expression Data: Fig. 3 from Ear et al., 2016
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Hatching:Long-pec (48.0h-60.0h)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa17420 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zf624 Small Deletion Exon 2 Premature Stop CRISPR
    zf625 Small Deletion Exon 2 Inframe Deletion CRISPR
    zf626 Indel Exon 2 Frameshift, Premature Stop CRISPR
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-rps14 1
    CRISPR2-rps14
    1
    MO1-rps14 N/A 2
    DISEASE ASSOCIATED WITH rps14 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    chromosome 5q deletion syndrome Alliance Macrocytic anemia, refractory, due to 5q deletion, somatic 153550
    DISEASE ASSOCIATED WITH rps14 VIA EXPERIMENTAL MODELS
    Human Disease Fish Conditions Citations
    chromosome 5q deletion syndrome rps14zf624/zf624 standard conditions Youn et al., 2019
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process erythrocyte maturation (more)
    Cellular Component ribosome (more)
    Molecular Function structural constituent of ribosome (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM rps14 No data available
    MARKER RELATIONSHIPS
    rps14 Encodes: [EST] fa92e08
    [cDNA] MGC:73215 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_200026 (1)
    Genomic GenBank:CU915785 (1) 83275 nt
    Select Tool
    Polypeptide UniProtKB:Q6PBW3 (1) 151 aa
    Sequence Information (all 11)
    ORTHOLOGY for rps14 ( Chr: 21 )
    CITATIONS (29)