Gene
gsnb
- ID
- ZDB-GENE-030131-8567
- Name
- gelsolin b
- Symbol
- gsnb Nomenclature History
- Previous Names
-
- gsnl
- gsnl2
- wu:fa92a06
- wu:fb15e01
- wu:fc14a07
- wu:fc28h09
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have actin filament binding activity and calcium ion binding activity. Predicted to be involved in actin filament severing; actin nucleation; and barbed-end actin filament capping. Human ortholog(s) of this gene implicated in Finnish type amyloidosis. Is expressed in several structures, including epidermis; hatching gland; otic vesicle; periderm; and sensory system. Orthologous to human GSN (gelsolin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 21 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6907352 (14 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Finnish type amyloidosis | Alliance | Amyloidosis, Finnish type | 105120 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | ADF-H/Gelsolin-like domain superfamily | Gelsolin-like domain | Villin/Gelsolin |
|---|---|---|---|---|
|
UniProtKB:F1QQQ5
|
728 | |||
|
UniProtKB:A4IGC2
|
728 |
Interactions and Pathways
No data available
Plasmids
No data available