Gene

gsnb

ID
ZDB-GENE-030131-8567
Name
gelsolin b
Symbol
gsnb Nomenclature History
Previous Names
  • gsnl
  • gsnl2
  • wu:fa92a06
  • wu:fb15e01
  • wu:fc14a07
  • wu:fc28h09
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have actin filament binding activity and phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in several processes, including actin filament severing; actin polymerization or depolymerization; and barbed-end actin filament capping. Predicted to localize to actin cytoskeleton; cytoplasm; and extracellular space. Is expressed in several structures, including epidermis; hatching gland; otic vesicle; periderm; and sensory system. Human ortholog(s) of this gene implicated in Finnish type amyloidosis. Orthologous to human GSN (gelsolin).
Genome Resources
Note
None
Expression
All Expression Data
21 figures from 3 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gsnb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Finnish type amyloidosis Alliance Amyloidosis, Finnish type 105120
Associated With gsnb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR007123 Gelsolin-like domain
Family IPR007122 Villin/Gelsolin
Family IPR030004 Gelsolin
Homologous_superfamily IPR029006 ADF-H/Gelsolin-like domain superfamily
Domain Details Per Protein
Protein Length ADF-H/Gelsolin-like domain superfamily Gelsolin Gelsolin-like domain Villin/Gelsolin
UniProtKB:A4IGC2 728
UniProtKB:F1QQQ5 728
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations