ZFIN ID: ZDB-GENE-030131-8373
Gene Name: collagen, type X, alpha 1a
Gene Symbol: col10a1a    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: col10a1, fa66d11 (1), wu:fa66d11 (1), wu:fb10c08

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Predicted to have extracellular matrix structural constituent. Involved in fin regeneration. Predicted to localize to extracellular matrix and extracellular space. Human ortholog(s) of this gene implicated in Schmid metaphyseal chondrodysplasia and osteochondrodysplasia. Is expressed in several structures, including cranium; fin; osteoblast; osteoprogenitor cell; and skeletal element. Orthologous to human COL10A1 (collagen type X alpha 1 chain).
Genome Resources: Alliance (1),  Gene:558919 (1),  Ensembl(GRCz11):ENSDARG00000054753 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la019933Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa12685 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa23025 Point Mutation Unknown Missense, Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa23026 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-col10a1a
    2
    CRISPR2-col10a1a
    2
    MO1-col10a1a N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH col10a1a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Schmid metaphyseal chondrodysplasia Alliance Metaphyseal chondrodysplasia, Schmid type 156500
    DISEASE ASSOCIATED WITH col10a1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process fin regeneration (more)
    Cellular Component collagen trimer (more)
    Molecular Function extracellular matrix structural constituent (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA col10a1a-201 (1)    Ensembl 2639
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM col10a1a
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(-2.2col10a1a:GFP) col10a1a GFP Danio rerio 1 4
    TgBAC(col10a1a:Citrine) col10a1a Citrine Danio rerio 1 6
    MARKER RELATIONSHIPS
    col10a1a Contained in: [BAC] CH211-266G18 (1)
    col10a1a Encodes: [EST] fa66d11, fb10c08
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001083827 (1) 2620 nt
    Genomic GenBank:CU306817 (1) 176617 nt
    Select Tool
    Polypeptide UniProtKB:A2RQR3 (1) 655 aa
    Sequence Information (all 16)
    ORTHOLOGY for col10a1a ( Chr: 17 )
    CITATIONS (99)