ZFIN ID: ZDB-GENE-030131-8228
Gene Name: hyperpolarization activated cyclic nucleotide-gated potassium channel 2b
Gene Symbol: hcn2b    Nomenclature History

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Previous Names: hcn2, si:dkey-28h18.1, wu:fj61d07

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 22 Mapping Details/Browsers
Description: Predicted to have voltage-gated potassium channel activity. Predicted to be involved in potassium ion transmembrane transport and regulation of ion transmembrane transport. Predicted to localize to integral component of membrane. Orthologous to human HCN2 (hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2).
Genome Resources: Alliance (1),  Gene:557285 (1),  Ensembl(GRCz11):ENSDARG00000061665 (2)
GENE EXPRESSION
All Expression Data: Fig. S3 from Trapani et al., 2011
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6705 Point Mutation Unknown Premature Stop ENU
sa43812 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa43813 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH hcn2b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH hcn2b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process ion transport (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ion channel activity (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA hcn2b-201 (1)    Ensembl 3136
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM hcn2b No data available
    MARKER RELATIONSHIPS
    hcn2b Contained in: [BAC] DKEY-28H18 (1) (order this), DKEYP-74C5 (1)
    hcn2b Encodes: [EST] fj61d07
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_680322 (1) 3218 nt
    Genomic GenBank:BX664631 (1) 220242 nt Blast at MegaBLAST
    Polypeptide UniProtKB:F1Q9R9 (1) 875 aa
    Sequence Information (all 16)
    ORTHOLOGY for hcn2b ( Chr: 22 )
    CITATIONS (20)