ZFIN ID: ZDB-GENE-030131-8179
Gene Name: retinoblastoma-like 1 (p107)
Gene Symbol: rbl1    Nomenclature History

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Previous Names: fj58e06, wu:fj58e06

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have RNA polymerase II activating transcription factor binding activity and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell differentiation and negative regulation of G1/S transition of mitotic cell cycle. Predicted to localize to chromatin and transcription regulator complex. Orthologous to human RBL1 (RB transcriptional corepressor like 1).
Genome Resources: Alliance (1),  Gene:795522 (1),  Ensembl(GRCz11):ENSDARG00000008141 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Cleavage:16-cell (1.5h-1.75h) to Pharyngula:Prim-5 (24.0h-30.0h)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa7051 Point Mutation Unknown Premature Stop ENU
sa8648 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa30879 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa33967 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40792 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-rbl1
    1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH rbl1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH rbl1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of cell cycle (more)
    Cellular Component nucleus (more)
    Molecular Function RNA polymerase II activating transcription factor binding (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA rbl1-201 (1)    Ensembl 3438
    rbl1-202 (1)    Ensembl 753
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM rbl1 No data available
    MARKER RELATIONSHIPS
    rbl1 Contained in: [BAC] DKEY-6E2 (1) (order this)
    rbl1 Encodes: [EST] fj58e06
    [cDNA] MGC:194424 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001130610 (1) 3439 nt
    Genomic GenBank:BX936390 (1) 168226 nt
    Select Tool
    Polypeptide UniProtKB:B3DI38 (1) 1058 aa
    Sequence Information (all 15)
    ORTHOLOGY for rbl1 ( Chr: 6 )
    CITATIONS (22)