Gene

eef2l2

ID
ZDB-GENE-030131-8112
Name
eukaryotic translation elongation factor 2, like 2
Symbol
eef2l2 Nomenclature History
Previous Names
  • fj53d02
  • si:ch211-113n10.4
  • wu:fj53d02
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have GTPase activity; ribosome binding activity; and translation elongation factor activity. Predicted to be involved in translational elongation. Predicted to localize to cytosol and ribonucleoprotein complex. Is expressed in brain and musculature system. Human ortholog(s) of this gene implicated in glaucoma and spinocerebellar ataxia type 26. Orthologous to human EEF2 (eukaryotic translation elongation factor 2).
Genome Resources
Note
None
Expression
All Expression Data
4 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With eef2l2 Human Ortholog
No data available
Associated With eef2l2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR031157 Tr-type G domain, conserved site
Domain IPR000640 Elongation factor EFG, domain V-like
Domain IPR000795 Translational (tr)-type GTP-binding domain
Domain IPR004161 Translation elongation factor EFTu-like, domain 2
Domain IPR005225 Small GTP-binding protein domain
Domain IPR005517 Translation elongation factor EFG/EF2, domain IV
Domain IPR041095 Elongation Factor G, domain II
Homologous_superfamily IPR009000 Translation protein, beta-barrel domain superfamily
Homologous_superfamily IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup
Homologous_superfamily IPR020568 Ribosomal protein S5 domain 2-type fold
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR035647 EF-G domain III/V-like
Domain Details Per Protein
Protein Length EF-G domain III/V-like Elongation factor EFG, domain V-like Elongation Factor G, domain II P-loop containing nucleoside triphosphate hydrolase Ribosomal protein S5 domain 2-type fold Ribosomal protein S5 domain 2-type fold, subgroup Small GTP-binding protein domain Translational (tr)-type GTP-binding domain Translation elongation factor EFG/EF2, domain IV Translation elongation factor EFTu-like, domain 2 Translation protein, beta-barrel domain superfamily Tr-type G domain, conserved site
UniProtKB:A2CE51 861
UniProtKB:Q6PC00 336
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations