Gene

cnksr2b

ID
ZDB-GENE-030131-8048
Name
connector enhancer of kinase suppressor of Ras 2b
Symbol
cnksr2b Nomenclature History
Previous Names
  • fj48e09
  • si:dkey-92k1.12
  • wu:fj48e09 (1)
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to be involved in regulation of signal transduction. Predicted to localize to cytoplasm and membrane. Human ortholog(s) of this gene implicated in syndromic X-linked mental retardation Hough type. Orthologous to human CNKSR2 (connector enhancer of kinase suppressor of Ras 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cnksr2b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
syndromic X-linked mental retardation Hough type Alliance Mental retardation, X-linked, syndromic, Houge type 301008
Associated With cnksr2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001478 PDZ domain
Domain IPR001660 Sterile alpha motif domain
Domain IPR001849 Pleckstrin homology domain
Domain IPR010599 Connector enhancer of kinase suppressor of ras 2
Domain IPR017874 CRIC domain
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR013761 Sterile alpha motif/pointed domain superfamily
Homologous_superfamily IPR036034 PDZ superfamily
Domain Details Per Protein
Protein Length Connector enhancer of kinase suppressor of ras 2 CRIC domain PDZ domain PDZ superfamily PH-like domain superfamily Pleckstrin homology domain Sterile alpha motif domain Sterile alpha motif/pointed domain superfamily
UniProtKB:A0A2R8RV71 869
UniProtKB:A0A0R4IFZ1 802
UniProtKB:E7FAZ0 963
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations