Gene

cul2

ID
ZDB-GENE-030131-8032
Name
cullin 2
Symbol
cul2 Nomenclature History
Previous Names
  • fj48a06
  • sb:eu1026
  • wu:fj48a06
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Predicted to have ubiquitin protein ligase binding activity and ubiquitin-protein transferase activity. Involved in chordate embryonic development and vasculature development. Predicted to localize to Cul2-RING ubiquitin ligase complex and SCF ubiquitin ligase complex. Orthologous to human CUL2 (cullin 2).
Genome Resources
Note
None
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Maeda et al., 2008
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cul2 Human Ortholog
No data available
Associated With cul2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR016157 Cullin, conserved site
Domain IPR001373 Cullin, N-terminal
Domain IPR016158 Cullin homology domain
Domain IPR019559 Cullin protein, neddylation domain
Homologous_superfamily IPR016159 Cullin repeat-like-containing domain superfamily
Homologous_superfamily IPR036317 Cullin homology domain superfamily
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
Homologous_superfamily IPR036390 Winged helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Cullin, conserved site Cullin homology domain Cullin homology domain superfamily Cullin, N-terminal Cullin protein, neddylation domain Cullin repeat-like-containing domain superfamily Winged helix DNA-binding domain superfamily Winged helix-like DNA-binding domain superfamily
UniProtKB:A0A286Y8D7 758
UniProtKB:E9QBK5 93
UniProtKB:E9QCA9 745
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations