Gene

gria4b

ID
ZDB-GENE-030131-8013
Name
glutamate receptor, ionotropic, AMPA 4b
Symbol
gria4b Nomenclature History
Previous Names
  • glur4b
  • fj46g06
  • wu:fj46g06
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have AMPA glutamate receptor activity and transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in glutamatergic synaptic transmission and modulation of chemical synaptic transmission. Predicted to localize to AMPA glutamate receptor complex; dendritic spine; and postsynaptic density membrane. Is expressed in nervous system; otic vesicle; and ventral mandibular arch. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human GRIA4 (glutamate ionotropic receptor AMPA type subunit 4).
Genome Resources
Note
None
Expression
All Expression Data
13 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gria4b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Neurodevelopmental disorder with or without seizures and gait abnormalities 617864
Associated With gria4b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001320 Ionotropic glutamate receptor
Domain IPR001828 Receptor, ligand binding region
Domain IPR019594 Ionotropic glutamate receptor, L-glutamate and glycine-binding domain
Family IPR001508 Ionotropic glutamate receptor, metazoa
Homologous_superfamily IPR028082 Periplasmic binding protein-like I
Domain Details Per Protein
Protein Length Ionotropic glutamate receptor Ionotropic glutamate receptor, L-glutamate and glycine-binding domain Ionotropic glutamate receptor, metazoa Periplasmic binding protein-like I Receptor, ligand binding region
UniProtKB:A0A2R8PVZ0 433
UniProtKB:B3DH33 904
UniProtKB:A0A2R8QDR4 904
UniProtKB:Q71E58 904
UniProtKB:A0A2R8QEE1 769
UniProtKB:F1QBT6 904
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations