ZFIN ID: ZDB-GENE-030131-7889
Gene Name: low density lipoprotein receptor-related protein 1Aa
Gene Symbol: lrp1aa    Nomenclature History

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Previous Names: lrp1a, si:dkey-40c23.4, wu:fj39b01

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Predicted to have calcium ion binding activity. Involved in regulation of vasculature development. Predicted to localize to integral component of membrane. Is expressed in blood vessel and caudal vein plexus. Human ortholog(s) of this gene implicated in Alzheimer's disease; myocardial infarction; and sciatic neuropathy. Orthologous to human LRP1 (LDL receptor related protein 1).
Genome Resources: Alliance (1),  Gene:563149 (1),  Ensembl(GRCz11):ENSDARG00000097827 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-lrp1aa N/A 1
MO2-lrp1aa N/A 1
DISEASE ASSOCIATED WITH lrp1aa HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
?Keratosis pilaris atrophicans 604093
DISEASE ASSOCIATED WITH lrp1aa VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process regulation of vasculature development (more)
Cellular Component integral component of membrane (more)
Molecular Function calcium ion binding (more)
GO Terms (all 4)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA lrp1aa-201 (1)    Ensembl 4949
lrp1aa-203 (1)    Ensembl 3571
lrp1aa-204 (1)    Ensembl 3053
lrp1aa-205 (1)    Ensembl 1685
lrp1aa-206 (1)    Ensembl 309
lrp1aa-207 (1)    Ensembl 582
Browsers: NCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM lrp1aa No data available
MARKER RELATIONSHIPS
lrp1aa Contained in: [BAC] DKEY-40C23 (1) (order this)
lrp1aa Encodes: [EST] fj39b01, IMAGE:7142928 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:XM_021479679 (1)
Genomic GenBank:CR407597 (1) 149133 nt
Select Tool
Polypeptide UniProtKB:A0A0H2UKL4 (1) 4505 aa
Sequence Information (all 34)
ORTHOLOGY for lrp1aa ( Chr: 11 )
CITATIONS (15)