Gene

osgep

ID
ZDB-GENE-030131-7880
Name
O-sialoglycoprotein endopeptidase
Symbol
osgep Nomenclature History
Previous Names
  • fj38e02
  • si:ch211-214j24.11 (1)
  • wu:fj38e02
  • zgc:112527
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to have N(6)-L-threonylcarbamoyladenine synthase activity and metal ion binding activity. Predicted to be involved in tRNA threonylcarbamoyladenosine modification. Predicted to localize to EKC/KEOPS complex; cytoplasm; and nucleus. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome 3. Orthologous to human OSGEP (O-sialoglycoprotein endopeptidase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With osgep Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Galloway-Mowat syndrome 3 Alliance Galloway-Mowat syndrome 3 617729
Associated With osgep Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017860 Peptidase M22, conserved site
Domain IPR000905 Gcp-like domain
Family IPR017861 Kae1/TsaD family
Family IPR034680 tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea and eukaryote
Homologous_superfamily IPR043129 ATPase, nucleotide binding domain
Domain Details Per Protein
Protein Length ATPase, nucleotide binding domain Gcp-like domain Kae1/TsaD family Peptidase M22, conserved site tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea and eukaryote
UniProtKB:Q5RHZ6 335
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations