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ZIRC
ZFIN ID: ZDB-GENE-030131-7806
Gene Name: integral membrane protein 2Cb
Gene Symbol: itm2cb
Sequence Ontology ID : SO:0000704

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Previous Names: itm2c, fj35c02, wu:fj35c02, zgc:66349

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(Including Attributions)
Location: Chr: 2 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have amyloid-beta binding activity. Predicted to be involved in negative regulation of amyloid precursor protein biosynthetic process. Predicted to localize to the Golgi apparatus and  ...
GENE EXPRESSION
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa17500 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH itm2cb HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH itm2cb VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of amyloid precursor protein biosynthetic process (more)
    Cellular Component integral component of membrane (more)
    Molecular Function amyloid-beta binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR007084 (1)
  • InterPro:IPR040145 (1)
  • PROSITE:PS50869 (1)
  • Pfam:PF04089 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA itm2cb-201 (1) 1857
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM itm2cb No data available
    MARKER RELATIONSHIPS
    itm2cbContained in: [BAC] CH211-195J11 (order this)
    itm2cbEncodes: [EST] fj35c02
    [cDNA] MGC:66349 (1) (order this), MGC:191768 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_199980 (1) 1823bp
    Genomic GenBank:BX890608 (1) 194388bp
    Select Tool
    Polypeptide UniProtKB:Q7SYK5 (1) 260aa
    Sequence Clusters UniGene:80266 (1)
    Sequence Information (all 17)
    ORTHOLOGY for itm2cb (Chr: 2)
    CITATIONS (17)