Gene

sulf2b

ID

ZDB-GENE-030131-775

Name

sulfatase 2b

Symbol

sulf2b Nomenclature History

Previous Names

sulf2a (1)
sulf2l
si:dkeyp-84g9.1
wu:fb48e04 (1)

Type

protein_coding_gene

Location

Chr: 23 Mapping Details/Browsers

Description

Predicted to have N-acetylglucosamine-6-sulfatase activity and glycosaminoglycan binding activity. Involved in epithelial structure maintenance. Predicted to localize to cell surface; endoplasmic reticulum; and plasma membrane. Is expressed in several structures, including central nervous system; head; neural rod; segmental plate; and somite. Orthologous to human SULF2 (sulfatase 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 4 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

Thisse Expression Data

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from Schenk et al., 2019
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With sulf2b Human Ortholog

No data available

Associated With sulf2b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR024607	Sulfatase, conserved site
Domain	IPR000917	Sulfatase, N-terminal
Domain	IPR024609	Extracellular sulfatase, C-terminal
Family	IPR014615	Extracellular sulfatase
Homologous_superfamily	IPR017850	Alkaline-phosphatase-like, core domain superfamily

Domain Details Per Protein

Protein	Length	Alkaline-phosphatase-like, core domain superfamily	Extracellular sulfatase	Extracellular sulfatase, C-terminal	Sulfatase, conserved site	Sulfatase, N-terminal
UniProtKB:F1R6U9 InterPro	867
UniProtKB:F1Q9W5 InterPro	868
UniProtKB:E9QHA8 InterPro	60
UniProtKB:F1R4H9 InterPro	321
UniProtKB:Q6EF97 InterPro	867
UniProtKB:F1QEE9 InterPro	885
UniProtKB:Q6EF98 InterPro	885

Transcripts

Genome Browsers

Type	Name	Length (nt)	Analysis
mRNA	sulf2b-201 (1) Ensembl	5114 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	sulf2b-202 (1) Ensembl	962 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	sulf2b-203 (1) Ensembl	2604 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	sulf2b-204 (1) Ensembl	321 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations