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ZIRC
ZFIN ID: ZDB-GENE-030131-774
Gene Name: cystathionase (cystathionine gamma-lyase)
Gene Symbol: cth
Sequence Ontology ID : SO:0000704

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Previous Names: fb58d08, wu:fb48e03 (1), wu:fb58d08 (1), zgc:66001 (1), zgc:85785

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(Including Attributions)
Location: Chr: 6 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have cystathionine gamma-lyase activity, cystathionine gamma-synthase activity, and pyridoxal phosphate binding activity; predicted to be involved in 'de novo' L-methionine biosynthetic  ...
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:66001]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la010139Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la025536Tg Transgenic Insertion Unknown Unknown DNA
    sa20749 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cth HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    cystathioninuria Cystathioninuria 219500
    Homocysteine, total plasma, elevated
    DISEASE ASSOCIATED WITH cth VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cysteine biosynthetic process via cystathionine (more)
    Cellular Component cytoplasm (more)
    Molecular Function catalytic activity (more)
    GO Terms (all 10)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cth-201 (1) 1828
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM cth No data available
    MARKER RELATIONSHIPS
    cthContained in: [BAC] DKEY-66A8 (1) (order this)
    cthEncodes: [EST] fb48e03, fb58d08
    [cDNA] MGC:66001 (order this), MGC:85785 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_212604 (1) 1844bp
    Genomic GenBank:BX324166 (1) 215450bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1QPF7 (1) 404aa
    Sequence Clusters UniGene:76994 (1)
    Sequence Information (all 20)
    ORTHOLOGY for cth (Chr: 6)
    CITATIONS (30)