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Gene

cox6a1

ID
ZDB-GENE-030131-7715
Name
cytochrome c oxidase subunit 6A1
Symbol
cox6a1 Nomenclature History
Previous Names
  • ns:zf-e250
  • zgc:103782
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to enable enzyme regulator activity. Predicted to be involved in mitochondrial electron transport, cytochrome c to oxygen. Predicted to be located in mitochondrial inner membrane. Predicted to be integral component of membrane. Predicted to be part of mitochondrial respiratory chain complex IV. Is expressed in several structures, including alar plate midbrain region; brain; eye; liver; and muscle. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease recessive intermediate D. Orthologous to human COX6A1 (cytochrome c oxidase subunit 6A1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cox6a1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Charcot-Marie-Tooth disease recessive intermediate D Alliance Charcot-Marie-Tooth disease, recessive intermediate D 616039
Associated With cox6a1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018507 Cytochrome c oxidase, subunit VIa, conserved site
Family IPR001349 Cytochrome c oxidase, subunit VIa
Homologous_superfamily IPR036418 Cytochrome c oxidase, subunit VIa superfamily
Domain Details Per Protein
Protein Length Cytochrome c oxidase, subunit VIa Cytochrome c oxidase, subunit VIa, conserved site Cytochrome c oxidase, subunit VIa superfamily
UniProtKB:A9C462 108
UniProtKB:Q642I9 108
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations