Gene
rapgef5a
- ID
- ZDB-GENE-030131-7681
- Name
- Rap guanine nucleotide exchange factor (GEF) 5a
- Symbol
- rapgef5a Nomenclature History
- Previous Names
-
- fk63g08
- fk78a01
- wu:fk63g08
- wu:fk78a01
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in Ras protein signal transduction. Predicted to act upstream of or within small GTPase-mediated signal transduction. Predicted to be active in plasma membrane. Orthologous to human RAPGEF5 (Rap guanine nucleotide exchange factor 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019804 | Ras guanine-nucleotide exchange factor, conserved site |
| Domain | IPR000651 | Ras-like guanine nucleotide exchange factor, N-terminal |
| Domain | IPR001895 | Ras guanine-nucleotide exchange factors catalytic domain |
| Family | IPR008937 | Ras-like guanine nucleotide exchange factor |
| Homologous_superfamily | IPR023578 | Ras guanine nucleotide exchange factor domain superfamily |
| Homologous_superfamily | IPR029071 | Ubiquitin-like domain superfamily |
| Homologous_superfamily | IPR036964 | Ras guanine-nucleotide exchange factor, catalytic domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Ras guanine-nucleotide exchange factor, catalytic domain superfamily | Ras guanine-nucleotide exchange factor, conserved site | Ras guanine nucleotide exchange factor domain superfamily | Ras guanine-nucleotide exchange factors catalytic domain | Ras-like guanine nucleotide exchange factor | Ras-like guanine nucleotide exchange factor, N-terminal | Ubiquitin-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0AB32T8F9 | InterPro | 480 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
rapgef5-201
(1)
|
Ensembl | 1,767 nt | ||
| mRNA |
rapgef5-202
(1)
|
Ensembl | 1,731 nt |
Interactions and Pathways
No data available
Plasmids
No data available