Gene
usp14
- ID
- ZDB-GENE-030131-7676
- Name
- ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
- Symbol
- usp14 Nomenclature History
- Previous Names
-
- wu:fk63d09
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable cysteine-type deubiquitinase activity and proteasome binding activity. Predicted to be involved in negative regulation of ERAD pathway. Predicted to act upstream of or within protein deubiquitination. Orthologous to human USP14 (ubiquitin specific peptidase 14).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018200 | Ubiquitin specific protease, conserved site |
| Conserved_site | IPR019954 | Ubiquitin conserved site |
| Domain | IPR000626 | Ubiquitin-like domain |
| Domain | IPR001394 | Peptidase C19, ubiquitin carboxyl-terminal hydrolase |
| Family | IPR044635 | Ubiquitin carboxyl-terminal hydrolase 14-like |
| Homologous_superfamily | IPR029071 | Ubiquitin-like domain superfamily |
| Homologous_superfamily | IPR038765 | Papain-like cysteine peptidase superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Papain-like cysteine peptidase superfamily | Peptidase C19, ubiquitin carboxyl-terminal hydrolase | Ubiquitin carboxyl-terminal hydrolase 14-like | Ubiquitin conserved site | Ubiquitin-like domain | Ubiquitin-like domain superfamily | Ubiquitin specific protease, conserved site |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q803B3 | InterPro | 489 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available