Gene

arl3b

ID
ZDB-GENE-030131-7518
Name
ADP ribosylation factor like GTPase 3b
Symbol
arl3b Nomenclature History
Previous Names
  • arl3
  • si:ch211-208d15.4
  • wu:fj22g05
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to have GTPase activity; microtubule binding activity; and purine ribonucleoside binding activity. Involved in cilium assembly. Predicted to localize to several cellular components, including microtubule cytoskeleton; midbody; and photoreceptor connecting cilium. Human ortholog(s) of this gene implicated in Joubert syndrome and retinitis pigmentosa. Orthologous to human ARL3 (ADP ribosylation factor like GTPase 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With arl3b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
retinitis pigmentosa 83 Alliance Retinitis pigmentosa 83 618173
Joubert syndrome 35 618161
Associated With arl3b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR005225 Small GTP-binding protein domain
Family IPR006689 Small GTPase superfamily, ARF/SAR type
Family IPR044612 ADP-ribosylation factor-like protein 2/3
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length ADP-ribosylation factor-like protein 2/3 P-loop containing nucleoside triphosphate hydrolase Small GTPase superfamily, ARF/SAR type Small GTP-binding protein domain
UniProtKB:A0A2R8RHH0 181
UniProtKB:B2GR26 182
UniProtKB:Q1MTE5 182
UniProtKB:A0A2R8QP23 97
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations