ZFIN ID: ZDB-GENE-030131-7512
Gene Name: si:dkeyp-75h12.2
Gene Symbol: si:dkeyp-75h12.2    Nomenclature History

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Previous Names: fj22e11, wu:fj22e11 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have protein serine/threonine kinase activity. Predicted to be involved in actin cytoskeleton organization and positive regulation of stress fiber assembly. Predicted to localize to the cytoplasm and nucleus. Orthologous to human TESK1 (testis associated actin remodelling kinase 1).
Genome Resources: Alliance (1),  Gene:559449 (1),  Ensembl(GRCz11):ENSDARG00000079281 (2)

Nomenclature Note: This gene is derived from the zebrafish genome sequencing and annotation project. When more is known about the gene, the current nomenclature will be replaced with more traditional zebrafish gene nomenclature. The prefix 'si:' indicates that this gene is represented by annotated genomic sequence from the Sanger Institute.

GENE EXPRESSION
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa44659 Point Mutation Unknown Unknown ENU
PHENOTYPE No data available
DISEASE ASSOCIATED WITH si:dkeyp-75h12.2 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH si:dkeyp-75h12.2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process protein phosphorylation (more)
Cellular Component cytoplasm (more)
Molecular Function ATP binding (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR000719 Protein kinase domain
Domain IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domain
Active_site IPR008266 Tyrosine-protein kinase, active site
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Family IPR015782 Dual specificity testis-specific protein kinase 1
Binding_site IPR017441 Protein kinase, ATP binding site
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA si:dkeyp-75h12.2-201 (1)    Ensembl 2859
ncRNA si:dkeyp-75h12.2-002 (1) 787
Browsers: NCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM si:dkeyp-75h12.2 No data available
MARKER RELATIONSHIPS
si:dkeyp-75h12.2 Contained in: [BAC] DKEYP-75H12 (1)
si:dkeyp-75h12.2 Encodes: [EST] fj22e11
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:XM_009303137 (1)
Genomic GenBank:CR318672 (1) 126789 bp
Select Tool
Polypeptide UniProtKB:E7FEW6 (1) 653 aa
Sequence Information (all 22)
ORTHOLOGY for si:dkeyp-75h12.2 ( Chr: 7 )
CITATIONS (14)