ZFIN ID: ZDB-GENE-030131-7503
Gene Name: NK-lysin tandem duplicate 4
Gene Symbol: nkl.4    Nomenclature History

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Previous Names: nkld (1), NK-lysin (1), si:rp71-40n14.1, wu:fj22b05 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Predicted to be involved in defense response to bacterium and lipid metabolic process. Is expressed in several structures, including caudal fin; gill; liver; myeloid cell; and pleuroperitoneal region. Orthologous to human GNLY (granulysin).
Genome Resources: Alliance (1),  Gene:335563 (1),  Ensembl(GRCz11):ENSDARG00000044023 (1)
GENE EXPRESSION
All Expression Data: 8 figures from 3 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la027895Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH nkl.4 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH nkl.4 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process defense response to bacterium (more)
    GO Terms (all 2)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA nkl.4-201 (1)    Ensembl 612
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nkl.4 No data available
    MARKER RELATIONSHIPS
    nkl.4 Contained in: [BAC] RP71-40N14 (1)
    nkl.4 Encodes: [EST] fj22b05
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_212741 (1) 503 nt
    Genomic GenBank:BX323450 (1) 178920 nt
    Select Tool
    Polypeptide UniProtKB:A0A2R8Q3N6 (1) 121 aa
    Sequence Information (all 12)
    ORTHOLOGY for nkl.4 ( Chr: 17 )
    CITATIONS (30)