ZFIN ID: ZDB-GENE-030131-7459
Gene Name: peptidylprolyl isomerase Ab (cyclophilin A)
Gene Symbol: ppiab    Nomenclature History

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Attributions

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Previous Names: ppial, cyclophilin (1), wu:fj18g05, zgc:73102, zgc:86688

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Predicted to have cyclosporin A binding activity and peptidyl-prolyl cis-trans isomerase activity. Involved in response to hypoxia. Predicted to localize to cytoplasm and intracellular membrane-bounded organelle. Is expressed in brain. Orthologous to human PPIA (peptidylprolyl isomerase A).
Genome Resources: Alliance (1),  Gene:335519 (1),  Ensembl(GRCz11):ENSDARG00000103994 (1)
GENE EXPRESSION
All Expression Data: 4 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:73102]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la017602Tg Transgenic Insertion Unknown Unknown DNA
sa8587 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41740 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ppiab HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ppiab VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process response to hypoxia (more)
    Cellular Component cytoplasm (more)
    Molecular Function isomerase activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ppiab No data available
    MARKER RELATIONSHIPS
    ppiab Encodes: [EST] fj18g05
    [cDNA] MGC:73102 (1), MGC:86688 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001328424 (1)
    Polypeptide UniProtKB:Q6PC53 (1) 164 aa
    Sequence Information (all 20)
    ORTHOLOGY for ppiab ( Chr: 10 )
    CITATIONS (59)