Gene

fuca1.1

ID
ZDB-GENE-030131-7434
Name
alpha-L-fucosidase 1, tandem duplicate 1
Symbol
fuca1.1 Nomenclature History
Previous Names
  • fuca1
  • wu:fj17c05
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to have alpha-L-fucosidase activity. Predicted to be involved in fucose metabolic process and glycoside catabolic process. Predicted to localize to lysosome. Is expressed in several structures, including EVL; epidermis; periderm; sensory system; and yolk syncytial layer. Human ortholog(s) of this gene implicated in fucosidosis. Orthologous to human FUCA1 (alpha-L-fucosidase 1).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fuca1.1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
fucosidosis Alliance Fucosidosis 230000
Associated With fuca1.1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018526 Glycoside hydrolase, family 29, conserved site
Domain IPR031919 Alpha-L-fucosidase, C-terminal
Family IPR000933 Glycoside hydrolase, family 29
Family IPR016286 Alpha-L-fucosidase, metazoa-type
Family IPR028755 Tissue alpha-L-fucosidase
Homologous_superfamily IPR013780 Glycosyl hydrolase, all-beta
Homologous_superfamily IPR017853 Glycoside hydrolase superfamily
Domain Details Per Protein
Protein Length Alpha-L-fucosidase, C-terminal Alpha-L-fucosidase, metazoa-type Glycoside hydrolase, family 29 Glycoside hydrolase, family 29, conserved site Glycoside hydrolase superfamily Glycosyl hydrolase, all-beta Tissue alpha-L-fucosidase
UniProtKB:Q6NY93 451
UniProtKB:Q7ZW80 451
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations