ZFIN ID: ZDB-GENE-030131-731
Gene Name: hyaluronan-mediated motility receptor (RHAMM)
Gene Symbol: hmmr    Nomenclature History

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Previous Name: wu:fb43e12

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 14 Mapping Details/Browsers
Description: Predicted to have hyaluronic acid binding activity. Involved in cardiac muscle tissue regeneration. Is expressed in proliferative region. Human ortholog(s) of this gene implicated in breast cancer. Orthologous to human HMMR (hyaluronan mediated motility receptor).
Genome Resources: Alliance (1),  Gene:322012 (1),  Ensembl(GRCz11):ENSDARG00000021794 (1)
GENE EXPRESSION
All Expression Data: 8 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2005 [eu686]
  6 figures (18 images) from Thisse et al., 2004 [IMAGE:7156302]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Hatching:Long-pec (48.0h-60.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa12528 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13903 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-hmmr N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH hmmr HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    breast cancer Alliance {Breast cancer, susceptibility to} 114480
    DISEASE ASSOCIATED WITH hmmr VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cardiac muscle tissue regeneration (more)
    Molecular Function hyaluronic acid binding (more)
    GO Terms (all 2)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA hmmr-202 (1)    Ensembl 3310
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM hmmr No data available
    MARKER RELATIONSHIPS
    hmmr Contained in: [BAC] DKEY-18F5 (1) (order this)
    hmmr Encodes: [EST] eu686 (1), fb43e12, IMAGE:7156302 (1)
    [cDNA] MGC:195330 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_199580 (1) 3273 nt
    Genomic GenBank:BX088535 (1) 197465 nt
    Select Tool
    Polypeptide UniProtKB:A0A0R4IPI0 (1) 904 aa
    Sequence Information (all 25)
    ORTHOLOGY for hmmr ( Chr: 14 )
    CITATIONS (24)