ZFIN ID: ZDB-GENE-030131-7282
Gene Name: ALG11 alpha-1,2-mannosyltransferase
Gene Symbol: alg11    Nomenclature History

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Previous Names: fj04e04, si:dkey-1h24.5, wu:fj04e04 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity. Predicted to be involved in oligosaccharide-lipid intermediate biosynthetic process and protein N-linked glycosylation. Predicted to localize to endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ip. Orthologous to human ALG11 (ALG11 alpha-1,2-mannosyltransferase).
Genome Resources: Alliance (1),  Gene:407614 (1),  Ensembl(GRCz11):ENSDARG00000031202 (1)
GENE EXPRESSION
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa12399 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa24848 Point Mutation Unknown Premature Stop ENU
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH alg11 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    congenital disorder of glycosylation Ip Alliance Congenital disorder of glycosylation, type Ip 613661
    DISEASE ASSOCIATED WITH alg11 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process mannosylation (more)
    Cellular Component endoplasmic reticulum (more)
    Molecular Function GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA alg11-201 (1)    Ensembl 2846
    alg11-202 (1)    Ensembl 690
    alg11-203 (1)    Ensembl 841
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM alg11 No data available
    MARKER RELATIONSHIPS
    alg11 Contained in: [BAC] DKEY-1H24 (1) (order this)
    alg11 Encodes: [EST] fj04e04
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001161351 (1)
    Genomic GenBank:BX005426 (1) 202018 nt Blast at MegaBLAST
    Polypeptide UniProtKB:F1R333 (1) 500 aa
    Sequence Information (all 18)
    ORTHOLOGY for alg11 ( Chr: 1 )
    CITATIONS (19)