ZFIN ID: ZDB-GENE-030131-7275
Gene Name: FKBP prolyl isomerase 1Aa
Gene Symbol: fkbp1aa    Nomenclature History

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Previous Names: fj02g10, wu:fj02g10, zgc:73373

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Predicted to have peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in chaperone-mediated protein folding and protein peptidyl-prolyl isomerization. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in Graves' disease. Orthologous to human FKBP1A (FKBP prolyl isomerase 1A) and FKBP1B (FKBP prolyl isomerase 1B).
Genome Resources: Alliance (1),  Gene:335335 (1),  Ensembl(GRCz11):ENSDARG00000022684 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:73373]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la016420Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH fkbp1aa HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH fkbp1aa VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process chaperone-mediated protein folding (more)
    Cellular Component cytoplasm (more)
    Molecular Function isomerase activity (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    aberrant processed transcript fkbp1aa-202 (1)    Ensembl 847
    mRNA fkbp1aa-201 (1)    Ensembl 805
    fkbp1aa-203 (1)    Ensembl 731
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM fkbp1aa No data available
    MARKER RELATIONSHIPS
    fkbp1aa Contained in: [BAC] DKEY-95O9 (1) (order this)
    fkbp1aa Encodes: [EST] fj02g10
    [cDNA] MGC:73373 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_199945 (1) 735 nt
    Genomic GenBank:CT737131 (1) 85330 nt
    Select Tool
    Polypeptide UniProtKB:Q6PBJ8 (1) 108 aa
    Sequence Information (all 17)
    ORTHOLOGY for fkbp1aa ( Chr: 8 )
    CITATIONS (25)