ZFIN ID: ZDB-GENE-030131-7171
Gene Name: fructose-1,6-bisphosphatase 1a
Gene Symbol: fbp1a    Nomenclature History

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Previous Names: fbp1l (1), fk92h02, wu:fk92h02, zgc:64096

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have fructose 1,6-bisphosphate 1-phosphatase activity. Predicted to be involved in several processes, including fructose 1,6-bisphosphate metabolic process; hexose metabolic process; and sucrose biosynthetic process. Predicted to localize to cytosol. Is expressed in female organism; intestine; lens; and solid lens vesicle. Human ortholog(s) of this gene implicated in fructose-1,6-bisphosphatase deficiency. Orthologous to human FBP1 (fructose-bisphosphatase 1).
Genome Resources: Alliance (1),  Gene:335231 (1),  Ensembl(GRCz11):ENSDARG00000021366 (2)
GENE EXPRESSION
All Expression Data: 8 figures from 4 publications
Directly Submitted Expression Data: 4 figures (3 images) from Thisse et al., 2004 [MGC:64096]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa16323 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH fbp1a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    fructose-1,6-bisphosphatase deficiency Alliance Fructose-1,6-bisphosphatase deficiency 229700
    DISEASE ASSOCIATED WITH fbp1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process carbohydrate metabolic process (more)
    Cellular Component cytoplasm (more)
    Molecular Function fructose 1,6-bisphosphate 1-phosphatase activity (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA fbp1a-201 (1)    Ensembl 1592
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM fbp1a No data available
    MARKER RELATIONSHIPS
    fbp1a Contained in: [BAC] DKEY-146L2 (1) (order this)
    fbp1a Encodes: [EST] fk92h02
    [cDNA] MGC:64096 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_199942 (1) 1638 nt
    Genomic GenBank:CR388096 (1) 139460 nt
    Select Tool
    Polypeptide UniProtKB:Q6PFT1 (1) 337 aa
    Sequence Information (all 19)
    ORTHOLOGY for fbp1a ( Chr: 5 )
    CITATIONS (33)